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female outbred hsd icr cd 1 mice  (Envigo)


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    Envigo female outbred hsd icr cd 1 mice
    Female Outbred Hsd Icr Cd 1 Mice, supplied by Envigo, used in various techniques. Bioz Stars score: 95/100, based on 214 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hsd+icr+cd+1+females/ICR+(CD-1)+outbred+mice/pmc12578323-65-0-11
    Average 95 stars, based on 214 article reviews
    female outbred hsd icr cd 1 mice - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Mouse Assay:

    Article Title: Trimeric polypeptide complexes comprising a collagen XVIII homotrimerization domain and/or a collagen xv homotrimerization and an agonist of a TNFR family costimulatory receptor, encoding polynucleotide thereof and method of use thereof to treat cancer
    Article Snippet: The cell lines were routinely screened for the absence of mycoplasma contamination by PCR using the Mycoplasma PlusTM Primer Set (Stratagene, Cedar Creek, TX, USA). .. Mice C57BL/6, BALB/c, Hsd:ICR (CD-1) and Hsd:athymic Nude-Foxn1 nu female mice were purchased from Harlan Iberica (Envigo, Barcelona, Spain). ..

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo.
    Article Snippet: .. Mice Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN). .. A colony of B6.129S6-Nlrp3tm1Bhk/J (The Jackson Laboratory; stock #021302; Nlrp3−/−) AR TIC LE IN PR ES S mice was established.

    Control:

    Article Title: Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery
    Article Snippet: .. Experimental and control animals were specific pathogen-free 8–12 week old females, body weight range 20–22 g. CD1 Swiss (Hsd:ICR) mice were obtained from Harlan Interfauna (Iberica, Spain). .. Immunodeficient NSG (NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz) mice were obtained from Charles River Laboratories (L’Arbresle, France, under license of The Jackson Laboratory, Bar Harbor, Maine, USA).

    other:

    Article Title: An acidic residue within the OCT4 dimerization interface of SOX17 is necessary and sufficient to overcome its pluripotency-inducing activity
    Article Snippet: B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J (OG2; Jackson Laboratory #004654 [Szabó et al., 2002]) mice and Hsd:ICR (CD-1) (ICR; Inotiv #030) mice were maintained at the Centre for ComparativeMedicine Research, The University of Hong Kong.

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo
    Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).



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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
    Female Hsd Icr Cd 1, supplied by Inotiv, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    mice female hsd icr cd 1  (Inotiv)
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    female outbred hsd icr cd 1 mice  (Envigo)
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    Envigo female outbred hsd icr cd 1 mice
    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    hsd icr cd 1 female mice  (Inotiv)
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    female hsd icr cd 1 mice  (Envigo)
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    hsd icr cd 1 female mice  (Envigo)
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    Envigo hsd icr cd 1 female mice
    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
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    Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

    Journal: Scientific Reports

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

    doi: 10.1038/s41598-025-34660-6

    Figure Lengend Snippet: Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

    Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

    Techniques: Activation Assay, Derivative Assay, Incubation, Enzyme-linked Immunosorbent Assay, Western Blot

    The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

    Journal: Scientific Reports

    Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

    doi: 10.1038/s41598-025-34660-6

    Figure Lengend Snippet: The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

    Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

    Techniques: Injection, Functional Assay